Erythema multiforme - ايريٿما ملٽيفارم
☆ 2022 ۾ جرمني مان Stiftung Warentest نتيجن، ModelDerm سان صارفين جي اطمينان صرف ادا ڪيل ٽيلي ميڊيسن مشوري جي ڀيٽ ۾ ٿورو گهٽ هئي.
Erythema multiforme minor ― نوٽ ڪريو ته زخمن جا مرڪز blanch ٿي سگهن ٿا.
Urticaria شايد هڪ فرق جي تشخيص جي طور تي سمجهي سگهجي ٿو.
References
Erythema multiforme (EM) اها حالت آهي جنهن ۾ مدافعتي رد عمل جي ڪري چمڙي ۽ مشڪ جھلي ٻنهي تي مخصوص نشانو نما داغ ظاهر ٿين ٿا. جيتوڻيڪ اڪثر وائرل انفڪشن، خاص طور تي هيپس سمپلڪس وائرس (HSV) ، يا ڪجهه دوائن جي ڪري، سبب ڪيترن ئي ڪيسن ۾ اڻڄاتل رهي ٿو. ايڪٽ اي ايم جو علاج ڪرڻ تي ڌيان ڏئي ٿو علامتن کي آسان ڪرڻ تي استعمال ڪندي ڪريمون جنهن ۾ اسٽيرائڊس يا اينٽي هينسٽامائن شامل آهن. بار بار EM کي منظم ڪرڻ تمام گهڻو اثرائتو آهي جڏهن هر مريض جي مطابق. ابتدائي طريقن ۾ زباني ۽ بنيادي علاج شامل آهن. انهن ۾ corticosteroids ۽ اينٽي وائرل دوائون شامل آهن. بنيادي علاج ۾ مضبوط اسٽيرائڊ ڪريم شامل آهن ۽ متاثر ٿيل مغز جھلي لاءِ حل. مريضن لاءِ اينٽي وائرلز لاءِ غير جوابده، سيڪنڊ-لائن جي اختيارن ۾ شامل آهن مدافعتي کي دٻائڻ واريون دوائون، اينٽي بايوٽڪڪس، اينٽيلمنٽيڪس، ۽ اينٽي مليريا.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
ڪيترين ئي صورتن ۾، نرمي erythema multiforme 2 کان 4 هفتن اندر پنهنجي پاڻ تي ختم ٿي ويندي آهي. Stevens-Johnson syndrome، هڪ سخت حالت جيڪا مغز جھلي کي متاثر ڪري ٿي، 6 هفتن تائين رهي سگهي ٿي. اسٽوڊيوز عام طور تي نرم ڪيسن لاء سفارش نه ڪئي وئي آهي. ڇا اسٽيرائڊس کي استعمال ڪيو وڃي سخت erythema multiforme لاءِ غير يقيني آهي ڇو ته بي ترتيب ٿيل مطالعي مان واضح نتيجا نه مليا آهن جن مان ظاهر ٿئي ٿو ته ڪهڙا ٻار هن علاج مان فائدو وٺندا.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
اسان هڪ ڪيس پيش ڪريون ٿا زباني erythema multiforme (EM) جو سبب TMP/SMX ، ڏيکاري ٿو عام زباني ۽ لپ السر بغير چمڙي جي زخمن جي. اهو ان کي ٻين زباني السر جي خرابين کان مختلف ڪرڻ جي ضرورت تي زور ڏئي ٿو. مريض کي علامتي علاج ۽ پريڊنيسولون گوليون مليون، جيڪي TMP/SMX تھراپي کي روڪڻ کان پوءِ سڌاري لاءِ آھن.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme هڪ ردعمل آهي جنهن ۾ چمڙي ۽ ڪڏهن ڪڏهن ميوڪوسا شامل آهي، مدافعتي نظام طرفان شروع ڪيو ويو آهي. عام طور تي، اهو ظاھر ٿئي ٿو ھدف جھڙو زخم، جيڪو ٿي سگھي ٿو اڪيلائي، ٻيهر، يا جاري رھي. اهي زخم عام طور تي انتهاپسندي، خاص طور تي انهن جي ٻاهرئين سطحن تي اثر انداز ڪن ٿا. بنيادي سببن ۾ شامل آهن انفيڪشن جهڙوڪ هيپس سمپلڪس وائرس ۽ ميڪوپلازما نمونيا، انهي سان گڏ ڪجهه دوائون، مدافعتي، ۽ آٽو ايميون بيماريون. Urticaria کان erythema multiforme فرق ڪرڻ زخمن جي مدت تي ڀاڙي ٿو؛ erythema multiforme زخم گهٽ ۾ گهٽ ست ڏينهن تائين مقرر رهندا آهن، جڏهن ته urticarial زخم اڪثر ڪري هڪ ڏينهن اندر غائب ٿي ويندا آهن. جيتوڻيڪ هڪجهڙائي آهي، اهو اهم آهي فرق ڪرڻ erythema multiforme کان وڌيڪ سخت اسٽيونس-جانسن سنڊروم، جيڪو عام طور تي پيش ڪري ٿو وسيع erythematous يا purpuric macules سان گڏ. انتظام erythema multiforme شامل آهي علامتي رليف سان لاڳاپيل اسٽيرائڊس يا اينٽي هسٽامائنز ۽ بنيادي سبب کي خطاب ڪرڻ. هيپس سادوڪس وائرس سان لاڳاپيل بار بار ڪيسن لاء، پروفيليڪڪ اينٽي وائرل علاج جي سفارش ڪئي وئي آهي. شديد ميوڪوسل شموليت شايد اسپتال ۾ داخل ٿيڻ جي ضرورت هجي اندروني سيال ۽ اليڪٽرولائيٽ متبادل.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
حالت هڪ نرم، خود محدود ريش کان هڪ سخت، زندگي جي خطري واري شڪل تائين مختلف ٿي سگهي ٿي، جنهن کي erythema multiforme major طور سڃاتو وڃي ٿو، جنهن ۾ مغز جھلي پڻ شامل آهي. بلغم جھلي جو حملو يا بلائن جي موجودگي شدت جون اهم نشانيون آهن.
- Erythema multiforme minor: عام ھدف يا اٿل، edematous papules acrally ورهايل
ٿلهي شڪل ۾ عام طور تي هلڪي خارش ٿيندي آهي (پر خارش تمام گهڻي شديد ٿي سگهي ٿي)، گلابي-ڳاڙهي داغ، هموار ترتيب سان ۽ انتها تي شروع ٿيندڙ. 7-10 ڏينهن اندر ريش جو حل بيماري جي هن شڪل ۾ معمول آهي.
- Erythema multiforme major: عام ھدف يا اٿل، edematous papules acraly distributed with an involvement of a or more mucous membranes. Epidermal detachment ۾ جسم جي مٿاڇري واري علائقي جو 10 سيڪڙو کان به گھٽ حصو شامل آھي.
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جيڪڏهن اهو بخار سان گڏ آهي (جسم جو گرمي پد وڌڻ)، اهو ممڪن آهي ته جلد ئي اسپتال جو دورو ڪرڻ جي سفارش ڪئي وئي آهي.
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